| In
this issue there is an emphasis on movement disorders, which is
no bad thing in my book.We begin with a superb review article on
the genetics of basal ganglia disorders by Patrick Chinnery and
David Burn. This lays out in a clear fashion the genes underlying
Parkinson’s disease and dystonia as well as discussing some
of the more recently discovered conditions - including the neuroferritinopathy
described first by this group. The authors go on to discuss the
importance of recognising the different genetic disorders of the
basal ganglia and suggest that it may be better to “think
of the genetics of neurological systems, rather than clinical features
or syndromes”.
The theme of genetic
disorders of the basal ganglia is taken up in the management section,
in which I discuss the approach to patients with chorea including
Huntington’s disease. I hope this sets out in a useful and
pragmatic fashion the many causes, and appropriate treatment, of
chorea. It is by no means complete but I hope of some help. To highlight
the way this field is moving forward there are a number of reviews
in the journal section on chorea.
The second review article
is on Korsakoff ’s syndrome. This rare complication of chronic
alcohol abuse is much talked about but rarely seen, so we are very
fortunate to have the contribution of Mike Kopelman and Mireia Pujol,
world leaders on this topic. The article is written from experience
and contains a wealth of insight. I am sure you will find this a
great short review of this fascinating topic.
The rehabilitation article
has taken as its theme the use of voice control as a means of operating
a range of electronic devices. This is a fascinating and sophisticated
area of support for patients with a range of disabilities, and is
surely an area that will evolve rapidly in the years to come. Finally,
Brian MacNamara, in his inimitable way, disentangles the confusion
in all of our minds about that mysterious ailment: the tarsal tunnel
syndrome.
As always, please
get in touch if you have a suggestion for a topic ACNR should review.
There are myriad facets of neuroscience we could look at. After
all: "If the brain were so simple we could understand it, we
would be so simple we couldn't" [Lyall Watson].
Roger
Barker
AdvancesinCNR@aol.com |