| Welcome
to another edition of ACNR which we hope continues to combine a
range of interesting and readable articles and items. This issue
begins with an excellent topical review on the neurological complications
of coeliac disease by Adrian Wills and Pengiran Tengah.This comes
at a time when the relevance and extent of gluten enteropathy to
a range of neurological conditions, especially cere-bellar ataxia
is being redefined, especially by the Sheffield group. Whatever
one thinks about the true incidence of these associations, it is
important to remember coeliac disease in a range of neurological
conditions, although the response to treatment is often disappointing.
Following
on from this controversial issue comes another on the cause of the
ALS- parkinsonian-dementia complex found in the Guam peninsula.
The development of this isolated cluster of neurological disease
has generated much interest from epidemiologists and neurologists
alike and with it a range of aetiological theories, of which the
latest developed by Cox and Sacks has recently been published in
Neurology and involves the eating of flying foxes. Huw Morris provides
an interesting commentary on this article, in particular to a series
of questions and answers that we posed and obtained from the
principal authors. Huw spent some time in Guam and is able to rely
on his own experiences and local knowledge and contacts to provide
the interesting counterpoint that forms his commentary.
We also have a useful update on the surgical treatment of dystonia
using stereotactic surgery, an area that is looking exciting and
may be of great therapeutic potential, especially given the paucity
of effective medical therapies. Obviously proper trials need to
be done to verify the approach (such as the randomised study already
started by Professor Aziz), to prevent the adoption of a therapeutic
strategy based on anecdote. We also have an excellent review from
Fergus Gracey on the affective problems of traumatic brain injury,
a topic that is often neglected, and an excellent historical account
of Phineas Gage by Larner and Leach.
There is our usual collection of anatomy primer, journal reviews,
conference and book reviews. Our regular Management feature is unfortunately
delayed this issue – as we go to press, Gillian Hall is imminently
expecting her second child. However, it will be back in September.
Talking of babies, we'd like to congratulate our Rehabilitation
Editor, Stephen Kirker, on the birth of baby Tom. Finally, we welcome
Patrick Chinnery to the journal review team. So there it is, another
action packed issue which you can read at leisure, now that those
tense sporting moments which dominated last month have finally passed!
Roger
Barker
AdvancesinCNR@aol.com |