From the Editor…

Posted in Editor's introduction on 18th Sep 2012

Have you ever thought of the immunopathology of different forms of multiple sclerosis (MS) being similar to that seen in the different forms of leprosy? Gavin Giovannoni in his stimulating article on primary progressive MS gives reasons as to why this may be the case, as he discusses the evidence for regarding this form of MS as a unique form of the condition.

The use of phenol to treat spasticity is not straightforward and Moheb Gaid lays out in great clarity how this agent can be used to target different nerves and muscle groups in patients with lower limb spasticity. He describes not only how best to effect the nerve block, but why one might consider doing it in the first place.

The diagnosis of epilepsy in adults can be very tricky and often relies on a good history and especially a witnessed account. In children it is no easier as Tekki Rao discusses in his article in our series on Paediatric Neurology. In his article he lays down the ground work by which a diagnosis can be made whilst also highlighting all the mimics of epilepsy that can easily be misdiagnosed.

The prognosis in patients with high grade gliomas (HGG) remains poor at only 12-18 months. Stephen Price and colleagues in their article for the Neurosurgery series discuss the latest thinking in these tumours and how we are beginning to better stratify gliomas using molecular markers which can then be used as prognostic indicators. In addition they discuss new ways by which to better delineate tumour margins and treat these malignant tumours.

Richard Kanaan really challenges us with the case he presents in the latest in the series on Clinical Dilemmas in Neuropsychiatry. The question that the case throws up is whether the patient is feigning their condition, and if so how can we prove it, what does it matter and finally what does that mean therapeutically. A must read!

The neural control of supranuclear eye movements is complex and trying to explain the range of pathways involved is a daunting prospect. However Janet Rucker shows us how to do this with a superbly clear account on this topic, with excellent illustrations and descriptions, that is hugely informative at so many different levels.

We have a bumper group of conference reports in this issue of ACNR, which contain much useful up-to-date information on a whole variety of neurological conditions.

Finally, we have a series of demands from UKABIF on what a life with brain injury should involve in terms of proper care and management, as well as our usual array of other reviews and news items.

So we hope you enjoy this new issue of the ACNR.

Roger Barker,  Co-Editor

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